Polyclonal antibody raised in rabbit against human KAT2B (Lysine Acetyltransferase 2B), using a synthetic peptide containing a sequence from the C-terminal part of the protein.
KAT2B
Reactivité: Humain, Souris
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ChIP/ChIP-seq 2 μg:ChIP WB 1:1,000
Restrictions
For Research Use only
Format
Liquid
Concentration
1 μg/μL
Buffer
Tris-citrate/phosphate buffer, 0.05 % azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Antigène
KAT2B
(K(lysine) Acetyltransferase 2B (KAT2B))
Autre désignation
KAT2B
Sujet
KAT2B (UniProtKB/Swiss-Prot entry Q92831) functions as a histone acetyltransferase, thereby promoting transcriptional activation. KAT2B binds with CBP and p300 where it competes with the adenoviral oncoprotein E1A for binding sites and as such counteracts the mitogenic activity of E1A. KAT2B also acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers.